In some cases, Kawasaki disease affects the coronary arteries, which carry oxygen-rich blood to the heart. As a result, a small number of children who have Kawasaki disease may develop serious heart problems. The cause of Kawasaki disease isn’t known. The body’s response to a virus or infection combined with genetic factors may cause the disease. However, no specific virus or infection has been found, and the role of genetics isn’t known.
One of the main symptoms of this disease is a fever that lasts longer than 5 days. The fever remains high even after treatment with standard childhood fever medicines. Children who have the disease also may have red eyes, red lips, and redness on the palms of their hands and soles of their feet. These are all signs of inflamed blood vessels. Early treatment is important. It helps reduce the risk that Kawasaki disease will affect the coronary arteries and cause more serious problems.
Kawasaki disease can’t be prevented. However, most children who develop Kawasaki disease fully recover—usually within weeks of getting symptoms. Further problems are rare. In some children, the disease affects the coronary arteries. This can cause serious problems. These children need long-term care and treatment. Researchers continue to look for the cause of Kawasaki disease and better ways to diagnose and treat it. They also hope to learn more about long-term health risks, if any, for people who have had the disease. ( Definition from nhlbi.nih.gov with “What is kawasaki’s disease” )